|
KMID : 0665220080210010001
|
|
Korean Journal of Food and Nutrition
2008 Volume.21 No. 1 p.1 ~ p.6
|
|
|
Effects of Job’s Tears(Yul-Moo) Extracts on Mouse Splenocyte and Macrophage Cell Activation
|
|
Ryu Hye-Sook
|
|
|
Abstract
|
|
|
|
Job’s Tears(Yul-Moo) is a grass crop long-used as a traditional medicine; it is also a nourishing food. There are reports of its anti-inflammatory, stomachic, antiallergic activity, and antispastic effects and Job’s Tears has been used in China to treat rheumatism, and neuralgia although its warts, rheumanism remains unclear. Thus, the present study was performed to investigate the in vitro effect of Job’s Tears extracts on immune function. Here mouse splenocyte proliferation and cytokine production(1L-1β, 1L-6, TNF-α )by peritoneal macrophages cultured with ethanol and water extracts of Job’s Tears were examined. splenocytes proliferation increased with Job’s Tears water extracts supplement at concentrations investigated The cytokine production (1L-1β, 1L-6, TNF-α ) by ELISA using a cytokine kit And 1L-1β, 1L-6 and TNF-α production increased water extracts supplementation. This in vitro study suggests that supplementation with Job’s Tears water extracts may enhance immune function by regulating the splenocyte proliferation and enhancing cytokine production of activated macrophages.
|
|
|
KEYWORD
|
|
|
splenocytes proliferation, Job’s Tears, cytokine1L-1β, IL-6TNF-α, immune.
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|